Fluctuating cholesterol and triglyceride levels in older adults are associated with a greater risk of Alzheimer's disease (AD) and Alzheimer's-related dementia (ADRD), a new study suggests.

Participants with the greatest variability in total cholesterol levels had a 19% increased risk for AD or ADRD within 12 years of baseline than those with stable levels. In addition, those with the highest variability in triglycerides had a 23% increased risk. The study did not differentiate between dementia types.

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